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Mass Spectrom. 11(9), 1067–1075. Urwin, V. , and Jackson, P. (1993). Anal. Biochem. 209(1), 57–62. , and Mann, M. (1994). Anal. Chem. 66, 3281–3287. , Degli-Esposti, M. , Johnson, R. , Smolak, P. , Waugh, J. , Timour, M. , Gerhart, M. , Schooley, K. , Smith, C. , Goodwin, R. , and Rauch, C. T. (1997). EMBOJ. 16(17), 5386–5397. Wilkins, M. , Sanchez, J. , Gooley, A. , Appel, R. , Hochstrasser, D. , and Williams, K. L. (1996). Biotechnol. Genet. Eng. Rev. 13, 19–50. Williams, E. R. (1996). J. Mass Spectrom.

G. (1982). Annu. Rev. Biochem. 51, 155–183. Yates, J. R. , Eng, J. , McCormack, A. , and Schieltz, D. (1995). Anal. Chem. 67(8), 1426–1436. , Herring, C. , Romano P. , Hinnebusch, A. , and Qin, J. (1998). Anal. Chem. 70(10), 2050–2059. PROTEIN SEQUENCE DATABASES By ROLF APWEILER SWISS-PROT Coordinator, EMBL Outstation–The European Bioinformatics Institute. Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom I. Introduction . . . . . . . . . . . . . . . . . . .

B. Production of TrEMBL . . . . . . . . . . . . . . . . . . . . . C. InterPro and EDITtoTrEMBL . . . . . . . . . . . . . . . . . . V. SWISS-PROT ϩ TrEMBL: A Complete and Nonredundant View on Protein World . . . . . . . . . . . . . . . . . . . . . . . . . . . VI. Specialized Protein Sequence Databases . . . . . . . . . . . . . . . A. MEROPS . . . . . . . . . . . . . . .

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