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By D.F. Swaab, E. Fliers, M. Mirmiran, W.A. Van Gool and F. Van Haaren (Eds.)

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Extra resources for Aging of the Brain and Alzheimer's Disease

Sample text

With respect to the differentiation of ‘normal’ aging from senile dementia, it is very difficult to discriminate between BSF and incipient dementia. Very recently, some authors have proposed the use of some newer methods to accomplish this discrimination. Much emphasis is given to the differentiation between active recall and passive recognition in learning tasks, and to the use of verbal tasks such as the ‘Nelson adult reading task’ (Nelson and McKenna, 1975), ‘category instance fluency’ tests (Branconnier and DeVitt, 1984) and computer-aided tests based upon an information processing paradigm (see below and Poon, 1983; Jolles, 1985).

E. the number of words that can be correctly recalled after a single presentation). Long-term memory is essential for this supra-span learning (Miller, 1972). The performance deficits discussed above have been interpreted in different ways. Memory processes could be involved but the impairments could also be a secondary consequence of an attentional deficit or impaired sensory memory. Furthermore, a decreased ability in the use of coding strategies is also probable: this notion is supported by the fact that acoustically presented material was coded less efficiently by demented patients (Miller, 1972).

Stowing, J. and Bicknell, J. M. (1979) Subcortical arteriosclerotic encephalopathy (Binswanger): computerized tomography. Neurology, 29: 1102-1 106. Sim, M. (1979)Early diagnosis of Alzheimer’s disease. In A. I. M. Glen and L. J. ), Alzheimer’s Disease. Early Recognition of Potentially Reversible Deficits, Churchill Livingstone, Edinburgh, pp. 78-85. Smith, J. S. and Kiloh, L. G. (1981) The investigation of dementia: results in 200 consecutive admissions. The Lancet, i: 824-827. , Paetau, A,, Wikstrom, J.

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