By William W. Cohen
This sensible advisor presents a succinct therapy of the final recommendations of cellphone biology, furnishing the pc scientist with the instruments essential to learn and comprehend present literature within the field.
The booklet explores 3 various features of biology: biological structures, experimental methods, and language and nomenclature. After a short advent to telephone biology, the textual content makes a speciality of the rules in the back of the most-widely used experimental systems and mechanisms, bearing on them to well-understood strategies in machine technological know-how.
The presentation of the cloth has been ready for the reader’s fast grab of the subject: reviews on nomenclature and historical past notes could be ascertained at a look, and crucial vocabulary is boldfaced through the textual content for simple identification.
Computer technological know-how researchers, pros and machine technological know-how scholars will locate this an incomparable source and a very good start line for a extra entire exam of cellphone biology.
"This concise booklet is a superb creation for machine scientists to the intriguing revolution less than manner in molecular biology. It presents lucid, high-level descriptions of the basic molecular mechanisms of existence, and discusses the computational ideas concerned. I want this little gem was once to be had while i used to be ‘learning the ropes’– it will were my first collection of analyzing material."
--Roni Rosenfeld, Carnegie Mellon University
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Extra info for A Computer Scientist's Guide to Cell Biology: A travelogue from a stranger in a strange land
To get enough information to determine the separation between pinholes, a microscope needs to capture rays from at least two diffraction orders. The aperature (width) of the microscope limits the angle between these to some θMAX and solving the equation above implies p > λ/sin θMAX Unless this holds, the two pinholes cannot be resolved. Figure 21. The Abbe model of resolution. William W. Cohen 39 (The figure ignores the issue of refractive index, which is the ratio of speed of light in the medium containing the specimen to the speed of light in air.
Good confocal microscopes can produce 3D images that include information from many different dyes. The confocal microscope was patented by Marvin Minsky (one of the founders of artificial intelligence) in 1957, but only became practical years later, with the development of lasers. Electron microscopes Electron microscopes use higher-fre- Mitochondria are organelles quency wavelengths, which gives them that produce energy from improved resolution, relative to optical glucose and oxygen. Actin is microscopes.
Coli produces lactose-importing proteins only when lactose is present, and glucose is not. Figure 10: How E. coli responds to nutrients 22 A Computer Scientist’s Guide to Cell Biology individual interactions can be quantitatively complex. To take an example, increases in glucose might increase the quantity of cAMP linearly—but often there will be complex non-linear relationships between the parts of a biological chemical pathway. The reason for this is that most biological reactions are mediated by enzymes—proteins that encourage a chemical change, without participating in that change.